N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester

CAS: 1334513-02-8

Ref. TR-P270355

Produktinformation

• Name: N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester
• Synonyme: (2s)-isopropyl-2-((perfluorophenoxyl)(phenoxy)phosphorylamino)Propanoate, (S)-2-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester, <span class="text-smallcaps">L</span>-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester, Isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-<span class="text-smallcaps">L</span>-alaninate, L-Alanine, N-[(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester, N-((S)-(2,3,4,5,6-Pentafluoro Phenoxy) Phenoxy Phosphinyl)-L--Alanine-1-Methyl Ethyl Ester, N-((S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl)-L-Alanine1-Methylethylester, N-[(S)-(2,3,4,5,6-Penta fluorophenoxy)phenoxy phosphinyl]-L-alanine 1-methylethyl ester, N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester, N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-<span class="text-smallcaps">L</span>-alanine 1-methylethyl ester, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine1-Methylethyl ester, Sofosbuvir Side Chain, Isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate, L-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester

Beschreibung

Applications N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is a reactant in the synthesis of phosphoramidate imidazo[2,1-f][1,2,4]triazine-4-amine adenosine prodrugs that can increase anti-HCV activity.
References Tyndall, E.M., et. al.: Bio. Med. Chem. Lett., 25, 869 (2015)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 453.3
• Formel: C₁₈H₁₇F₅NO₅P
• Farbe/Form: Neat
• InChl: InChI=1S/C20H23F5NO4P.O/c1-11(2)28-20(27)12(3)26-31(4,5,29-13-9-7-6-8-10-13)30-19-17(24)15(22)14(21)16(23)18(19)25;/h6-12,26H,1-5H3;/t12-;/m0./s1
• InChI Key: InChIKey=PCPLMRKVBFMLEU-YDALLXLXSA-N
• SMILES: CC(C)OC(=O)[C@H](C)NP(C)(C)(Oc1ccccc1)Oc1c(F)c(F)c(F)c(F)c1F.[O]