Perphenazine-d8 Dihydrochloride

CAS: 2070015-23-3

Ref. TR-P291102

Produktinformation

• Name: Perphenazine-d8 Dihydrochloride
• Synonyme: 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-(piperazine-d8)ethanol Dihydrochloride, 1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl) propyl]piperazine-d8-Dihydrochloride, Chloriprozine-d8, Chlorperphenazine-d8, Decentan-d8, Emesinal-d8, Etaperazin-d8, Perfenil-d8, Perphenan-d8, Perphenazin-d8, Sch 3940-d8, Thilatazin-d8
• CAS: 2070015-23-3

Beschreibung

Applications Labelled Perphenazine. D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
References Gaertner, H.J., et al.: Drug Metab. Dispos., 3, 437 (1975), O Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 484.94
• Formel: C₂₁H₂₀D₈Cl₃N₃OS
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2/i10D2,11D2,12D2,13D2
• InChI Key: InChIKey=RGCVKNLCSQQDEP-BGKXKQMNSA-N
• SMILES: [2H]C1([2H])N(CCO)C([2H])([2H])C([2H])([2H])N(CCCN2c3ccccc3Sc3ccc(Cl)cc32)C1([2H])[2H]