Perphenazine Sulfoxide

CAS: 10078-25-8

Ref. TR-P291105

Produktinformation

• Name: Perphenazine Sulfoxide
• Synonyme: Perphenazine Imp. A (EP), 2-[4-[3-(2-Chloro-5-oxido-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, Perphenazine Sulphoxide, Perphenazine Impurity A, 1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-, S-oxide, 1-Piperazineethanol, 4-[3-(2-chloro-5-oxido-10H-phenothiazin-10-yl)propyl]-, 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, S-oxide, 2-Chloro-10-(3-(4-(2-Hydroxyethyl)-7-Piperazinyl)Propyl)Phenothiazine, 2-{4-[3-(2-chloro-5-oxido-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol, 4-(3-(2-Chlorophenothiazin-10-Yl)Propyl)-1-Piperazineethanosulfoxide, 4-[3-(2-Chloro-5-oxido-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol, Ethaperazine sulfoxide, Perphenazine sulfoxide

Beschreibung

Impurity Perphenazine EP Impurity A
Applications Perphenazine Sulfoxide (Perphenazine EP Impurity A) acts as a D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
References Gaertner, H.J., et al.: Drug Metab. Dispos., 3, 437 (1975), O Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 419.97
• Formel: C₂₁H₂₆ClN₃O₂S
• Farbe/Form: Neat
• InChl: InChI=1S/C21H26ClN3O2S/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)28(21)27)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
• InChI Key: InChIKey=WXJXTMQMAOYROI-UHFFFAOYSA-N
• SMILES: O=S1c2ccccc2N(CCCN2CCN(CCO)CC2)c2cc(Cl)ccc21