Pilaralisib

CAS: 934526-89-3

Ref. TR-P441390

Produktinformation

• Name: Pilaralisib
• Synonyme: 2-amino-N-(3-(N-(3-((2-Chloro-5-methoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-2-methylpropanamide, 2-Amino-N-[3-[N-[3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide, 2-Amino-N-[3-[[3-(2-chloro-5-methoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide, 2-Amino-N-[3-[[[3-[(2-chloro-5-methoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-2-methylpropanamide, 3-Cyano-5-fluorobenzaldehyde, 3-Fluoro-5-formylbenzonitrile, Benzonitrile, 3-fluoro-5-formyl-, N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide, N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide, Propanamide, 2-amino-N-[3-[[[3-[(2-chloro-5-methoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-2-methyl-, SC, Sar 245408, Sar245408, Xl-147, Xl147

Beschreibung

Applications Pilaralisib is a pan-PI3K inhibitor used in the treatment of patients with chronic lymphocytic leukemia or relapsed or refractory lymphoma.
References Brown, J. et alClin. Cancer Res., 21, 3160 (2015);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 541.02
• Formel: C₂₅H₂₅ClN₆O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C25H25ClN6O4S/c1-25(2,27)24(33)28-15-7-6-8-17(13-15)37(34,35)32-23-22(29-19-9-4-5-10-20(19)30-23)31-21-14-16(36-3)11-12-18(21)26/h4-14H,27H2,1-3H3,(H,28,33)(H,29,31)(H,30,32)
• InChI Key: InChIKey=QINPEPAQOBZPOF-UHFFFAOYSA-N
• SMILES: COc1ccc(Cl)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cccc(NC(=O)C(C)(C)N)c2)c1