2-Piperidin-4-yl-1H-benzimidazole

CAS: 38385-95-4

Ref. TR-P482075

Produktinformation

• Name: 2-Piperidin-4-yl-1H-benzimidazole
• Synonyme: 2-(4-Piperidinyl)-1H-benzimidazole, 2-(Piperidin-4-yl)benzimidazole, 4-(Benzimidazol-2-yl)piperidine, 1H-benzimidazole, 2-(4-piperidinyl)-, 2-(4-Piperidinyl)-1H-benzimidazol, 2-(4-Piperidyl)-1H-benzimidazole, 2-(Piperidin-4-yl)-1H-1,3-benzodiazole, 2-(Piperidin-4-yl)-1H-benzo[d]imidazole, 2-Piperidin-4-Yl-1H-Benzoimidazole

Beschreibung

Applications 2-Piperidin-4-yl-1H-benzimidazole is used as a reagent in the synthesis of 3-amino-1-(5-indanyloxy)-2-propanol derivatives as potent sodium channel blockers for the treatment of ischemic stroke. Also used as a reagent in the synthesis of 2,3,5-trisubstituted pyridine derivatives as potent Akt1/Akt2 dual inhibitors.
References Seki, M., et al.: Chem. Pharm. Bull., 60, 488 (2012); Zhao, Z., et al.: Bioorg. Med. Chem. Lett., 15, 905 (2005)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 201.27
• Formel: C₁₂H₁₅N₃
• Farbe/Form: Neat
• InChl: InChI=1S/C12H15N3/c1-2-4-11-10(3-1)14-12(15-11)9-5-7-13-8-6-9/h1-4,9,13H,5-8H2,(H,14,15)
• InChI Key: InChIKey=HBOGHPAOOWUTLB-UHFFFAOYSA-N
• SMILES: c1ccc2[nH]c(C3CCNCC3)nc2c1