nPOC-POC Tenofovir(Mixture of Diastereomers)

CAS: 1217542-13-6

Ref. TR-P680500

Produktinformation

• Name: nPOC-POC Tenofovir(Mixture of Diastereomers)
• Synonyme: 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid (1-methylethyl,propyl) Ester 5-Oxide, nPOC-POC PMPA
• Marke: TRC

Beschreibung

Applications An impurity of Tenofovir (T018500(P)). Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);

Chemische Eigenschaften

• Molekulargewicht: 519.44
• Formel: C₁₉H₃₀N₅O₁₀P
• Farbe/Form: Neat
• InChl: InChI=1S/C19H30N5O10P/c1-5-6-28-18(25)29-10-32-35(27,33-11-30-19(26)34-13(2)3)12-31-14(4)7-24-9-23-15-16(20)21-8-22-17(15)24/h8-9,13-14H,5-7,10-12H2,1-4H3,(H2,20,21,22)/t14-,35?/m1/s1
• InChI Key: InChIKey=GTLFLMZOABSJSV-UHFFFAOYSA-N
• SMILES: Nc1cnccc1Cl