Pomalidomide-(d4 major)

CAS: 1416575-78-4

Ref. TR-P688202

Produktinformation

• Name: Pomalidomide-(d4 major)
• Synonyme: 4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione-d4, 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione-d4, Actimid-d4, CC 4047-d4, IMiD 3-d4

Beschreibung

Applications Pomalidomide-d4 is the labeled anaxlogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 277.27
• Formel: C₁₃H₇D₄N₃O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)/i4D2,5D2
• InChI Key: InChIKey=UVSMNLNDYGZFPF-CQOLUAMGSA-N
• SMILES: [2H]C1([2H])C(=O)NC(=O)C(N2C(=O)c3cccc(N)c3C2=O)C1([2H])[2H]