Prasugrel Hydroxy Thiolactone

CAS: 947502-66-1

Ref. TR-P701160

Produktinformation

• Name: Prasugrel Hydroxy Thiolactone
• Synonyme: 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxy thieno[3,2-c]pyridin-2(4H)-one

Beschreibung

Applications Prasugrel Hydroxy Thiolactone, is the metabolite of Prasugrel (P701150), which is a novel thienopyridine. It is also a potent inhibitor of platelet aggregation in vivo.
References Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 347.4
• Formel: C₁₈H₁₈FNO₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C18H18FNO3S/c19-14-4-2-1-3-13(14)16(17(22)11-5-6-11)20-8-7-18(23)12(10-20)9-15(21)24-18/h1-4,9,11,16,23H,5-8,10H2
• InChI Key: InChIKey=OHANBBNBMKFHBI-UHFFFAOYSA-N
• SMILES: O=C1C=C2CN(C(C(=O)C3CC3)c3ccccc3F)CCC2(O)S1