Pravastatin 6'-Ketone Sodium Salt

CAS: 201423-59-8

Ref. TR-P702050

Produktinformation

• Name: Pravastatin 6'-Ketone Sodium Salt
• Synonyme: (βR,δR,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-6-oxo-1-naphthaleneheptanoic Acid Sodium Salt, [1α(βS*,δS*),2α,8β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-6-oxo-1-naphthaleneheptanoic Acid Sodium Salt, R 104 Sodium Salt, Pravastatin Impurity
• CAS: 201423-59-8

Beschreibung

Stability Very Hygroscopic, Temperature Sensitive
Applications Pravastatin 6'-Ketone Sodium Salt is an impurity of Pravastatin Sodium (P702000), which is a competitive inhibitor of HMG-CoA reductase. It can be used as a drug to for lowering cholesterol and preventing cardiovascular disease.
References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), Yoshino, G., et al.: Lancet, 2, 740 (1986), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 444.49
• Formel: C₂₃H₃₃NaO₇
• Farbe/Form: White to Yellow Solid
• InChl: InChI=1S/C23H34O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16,18-20,22,24,26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,18+,19-,20-,22-;/m0./s1
• InChI Key: InChIKey=IFUGZZMUALSRRZ-OJURZSSNSA-M
• SMILES: CC[C@H](C)C(=O)O[C@H]1CC(=O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O[Na])[C@H]21