L-Propoxyphene-d5 HCl (propionyl-d5)

CAS: 1276197-49-9

Ref. TR-P831512

Produktinformation

• Name: L-Propoxyphene-d5 HCl (propionyl-d5)
• Synonyme: rac-Dextropropoxyphene D5 (propionyl-D5) hydrochloride, (±)-Dextropropoxyphene-D5 (propanoyl-D5) hydrochloride, (±)-Propoxyphene-d5 hydrochloride, (αS)-rel-α-[(1R)-2-(Dimethylamino)-1-methylethyl]-α-phenylbenzeneethanol 1-propanoate-2,2,3,3,3-d5 hydrochloride, (2RS,3SR)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate-d5 (ester) hydrochloride, rel-(αS)-α-[(1R)-2-(Dimethylamino)-1-methylethyl]-α-phenylbenzeneethanol propanoate-d5 (ester) hydrochloride
• Marke: TRC
• Beschreibung: Applications L-Propoxyphene-d5 Hydrochloride is the isotope labelled analog and L-isomer of Propoxyphene Hydrochloride (P831500); a controlled substance (opiate) and analgesic (narcotic). The α-DL-and D-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive. Oral administration of L-Propoxyphene Hydrochloride enhances the analgesic activity of D-Propoxyphene Hydrochloride.References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971); McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972); Murphy, P.J., et al.: J. Pharmacol. Exp. Ther., 199, 415 (1976)

Chemische Eigenschaften

• Molekulargewicht: 380.96
• Formel: C₂₂H₂₅D₅ClNO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C22H29NO2.ClH/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19;/h6-15,18H,5,16-17H2,1-4H3;1H/t18-,22+;/m1./s1/i1D3,5D2
• InChI Key: InChIKey=UPWWMRQTWKAIAM-UHFFFAOYSA-N
• SMILES: CC.Cc1ccc2c(c1)C(=O)C1C=CC=CC1C2=O