Proscillaridin A

CAS: 466-06-8

Ref. TR-P838495

Produktinformation

• Name: Proscillaridin A
• Synonyme: Bufa-4,20,22-trienolide, 3-[(6-deoxy-a-L-mannopyranosyl)oxy]-14-hydroxy-, (3ß)-, Proscillaridin A (6CI,7CI,8CI), (3ß)-3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide, 14-Hydroxy-3ß-(rhamnosyloxy)bufa-4,20,22-trienolide, 3ß-Rhamnosido-14ß-hydroxy-?4,20,22-bufatrienolide, 3ß-[(6-Deoxy-a-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide, A 32686, Caradrin, Cardion, Cardiovite, Carmazon, Coratol, Desglucotransvaaline, Desglucotrnasvaaline, Herzo Proscillan, NSC 7521, PSC-801, Procardin, Procilan, Proscillan, Proscillaridin, Proslladin, Prostosin, Proszine, Protasin, Purosin-TC, Sandoscill, Scillacrist, Scillarenin 3ß-rhamnoside, Simeon, Solestril, Stellarid, Talucard, Talusin, Tradenal, Transvaalin, degluco-, Urgilan, Wirnesin, (3Beta)-3-[(6-Deoxyhexopyranosyl)Oxy]-14-Hydroxybufa-4,20,22-Trienolide, (3Beta,8Xi,9Xi)-3-[(6-Deoxyhexopyranosyl)Oxy]-14-Hydroxybufa-4,20,22-Trienolide, (3beta)-3-[(6-deoxy-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide, (3beta)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide, (3β)-3-[(6-Deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide, 14-Hydroxy-3β-(rhamnosyloxy)bufa-4,20,22-trienolide, 3β-Rhamnosido-14β-hydroxy-Δ^4,20,22-bufatrienolide, 3β-[(6-Deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide, Bufa-4,20,22-trienolide, 3-[(6-deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-14-hydroxy-, (3β)-, Psc-801, Scillarenin 3β-rhamnoside, Transvaalin, degluco-, Bufa-4,20,22-trienolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-14-hydroxy-, (3β)-, (3β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14-hydroxybufa-4,20,22-trienolide

Beschreibung

Applications Proscillaridin A is a cardiac glycoside that can be used to treat congestive heart failure and cardiac arrhythmia. In addition, Proscillaridin A also inhibit breast cancer MCF-7 cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Prassas, I. and Diamandis, E. P.: Nat. Rev. Drug Discov. 7, 926 (2008); Milutinovic, S., et al.: PloS One 11, e0152692/1 (2016); Bielawski, K., et al.: ?Biol. Pharm. Bull 29, 1493 (2006)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 530.65
• Formel: C₃₀H₄₂O₈
• Farbe/Form: Neat
• InChl: InChI=1S/C30H42O8/c1-16-24(32)25(33)26(34)27(37-16)38-19-8-11-28(2)18(14-19)5-6-22-21(28)9-12-29(3)20(10-13-30(22,29)35)17-4-7-23(31)36-15-17/h4,7,14-16,19-22,24-27,32-35H,5-6,8-13H2,1-3H3/t16-,19-,20+,21-,22+,24-,25+,26+,27-,28-,29+,30-/m0/s1
• InChI Key: InChIKey=MYEJFUXQJGHEQK-ALRJYLEOSA-N
• SMILES: C[C@@H]1O[C@@H](O[C@@H]2C=C3CC[C@@H]4[C@H](CC[C@]5(C)[C@@H](c6ccc(=O)oc6)CC[C@]45O)[C@@]3(C)CC2)[C@H](O)[C@H](O)[C@H]1O