Prucalopride Succinate

CAS: 179474-85-2

Ref. TR-P838950

Produktinformation

• Name: Prucalopride Succinate
• Synonyme: Butanedioic acid, compd. with 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1), 7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-, butanedioate (1:1) (9CI), R 108512, Resolor, Resotran, Prucalopride INTERMEDIATES, Prucalopride succinate

Beschreibung

Applications Prucalopride is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 485.96
• Formel: C₁₈H₂₆ClN₃O₃·C₄H₆O₄
• Farbe/Form: Neat
• InChl: 5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23), 1-2H2,(H,5,6)(H,7,8), InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14
• InChI Key: InChIKey=QZRSNVSQLGRAID-UHFFFAOYSA-N
• SMILES: COCCCN1CCC(NC(=O)c2cc(Cl)c(N)c3c2OCC3)CC1.O=C(O)CCC(=O)O