β-Pseudouridine-13C, 15N2

CAS: 1445-07-4

Ref. TR-P839607

Produktinformation

• Name: β-Pseudouridine-13C, 15N2
• Synonyme: 5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione-13C, 15N2, 5-(β-D-Ribofuranosyl)uracil-13C, 15N2, 5-Ribosyluracil-13C, 15N2, NSC 162405-13C, 15N2, Pseudouridine C, β-D-Pseudouridine-13C, 15N2, Pseudouridine-13C, 15N2, ψ-Uridine-13C
• Marke: TRC
• Beschreibung: Applications Isotope labelled β-Pseudouridine is an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called Ψ synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.References Ferré-D'Amaré A.R. et al.: Curr. Opin. Struct. Biol., 13, 49 (2003); Hamma, T. et al.: Chem. Biol., 13, 1125 (2006); Liang, X.H. et al.: RNA, 8, 237 (2002); Monobe, M. et al.: Mut. Res. Gen. Toxicol. Env. Mutagen., 538, 93 (2003)

Chemische Eigenschaften

• Molekulargewicht: 247.18
• Formel: C₈CH₁₂N₂O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/m1/s1/i9+1,10+1,11+1
• InChI Key: InChIKey=PTJWIQPHWPFNBW-FYLXHLGQSA-N
• SMILES: O=c1[15nH][13c](=O)[15nH]cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O