Pyrimidin-4-ylboronic Acid (~80%)

CAS: 852362-24-4

Ref. TR-P997335

Produktinformation

• Name: Pyrimidin-4-ylboronic Acid (~80%)
• Synonyme: 4-pyrimidinylboronic Acid, 852362-24-4, B-4-Pyrimidinylboronic acid, Boronic acid, 4-pyrimidinyl-, Boronic acid, B-4-pyrimidinyl-, Pyrimidin-4-ylboronic acid

Beschreibung

Applications Pyrimidin-4-ylboronic Acid is an intermediate used to prepare aldosterone synthase inhibiting pyrimidinylnaphthalenes via Suzuki cross-coupling reactions. It is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine as a potent, orally active Src kinase inhibitor with antitumor activity.
References Voets, M., et al.; J. Med. Chem., 48, 6632 (2005); Noronha, G., et al.: Bioorg. Med. Chem. Lett., 17, 602 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 123.91
• Formel: C₄H₅BN₂O₂
• Reinheit: ~80%
• Farbe/Form: Neat
• InChl: InChI=1S/C4H5BN2O2/c8-5(9)4-1-2-6-3-7-4/h1-3,8-9H
• InChI Key: InChIKey=YQEFFTJDRKXKAP-UHFFFAOYSA-N
• SMILES: OB(O)c1ccncn1