Queuine Hydrochloride

CAS: 72496-59-4

Ref. TR-Q525000

Produktinformation

• Name: Queuine Hydrochloride
• Synonyme: 2-Amino-5-[[[(1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl]amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Dihydrochloride, [1S-(1a,4ß,5ß)]-2-Amino-5-[[(4,5- dihydroxy-2-cyclopenten-1-yl)amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Hydrochloride, 2-amino-5-((((1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-4H-pyrrolo(2,3-d)pyrimidin-4-one, 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[(4,5-dihydroxy-2-cyclopenten-1-yl)amino]methyl]-1,7-dihydro-, [1S-(1α,4β,5β)]-, 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[[(1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl]amino]methyl]-1,7-dihydro-, Queuine

Beschreibung

Applications It is one of the modified base which is found at first anticodon position of specific tRNAs. Queuine promotes cell death and participates in regulation of cell proliferation.
References Katze, J., et al.: Biochemistry, 23, 1171 (1984), Reisser, T., et al.: Eur. J. Biochem., 221, 979 (1994), Jin, Z., et al.: J. Biol. Chem., 281, 14446 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 277.283646
• Formel: C₁₂H₁₅N₅O₃·(ClH)x
• Farbe/Form: Neat
• InChl: InChI=1S/C12H15N5O3/c13-12-16-10-8(11(20)17-12)5(4-15-10)3-14-6-1-2-7(18)9(6)19/h1-2,4,6-7,9,14,18-19H,3H2,(H4,13,15,16,17,20)/t6-,7-,9+/m0/s1
• InChI Key: InChIKey=WYROLENTHWJFLR-ACLDMZEESA-N
• SMILES: Nc1nc(=O)c2c(CN[C@H]3C=C[C@H](O)[C@@H]3O)c[nH]c2[nH]1