Quinacrine Dihydrochloride

CAS: 69-05-6

Ref. TR-Q550610

Produktinformation

• Name: Quinacrine Dihydrochloride
• Synonyme: Mepacrine Hydrochloride, 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, hydrochloride (1:2), 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dihydrochloride (9CI), Acridine, 6-chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxy-, dihydrochloride (8CI), 2-Chloro-5-(?-diethylamino-a-methylbutylamino)-7-methoxyacridine dihydrochloride, 2-Methoxy-6-chloro-9-(4-diethylamino-1-methylbutylamino)acridine dihydrochloride, 3-Chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine dihydrochloride, 3-Chloro-9-(4'-diethylamino-1'-methylbutylamino)-7-methoxyacridine dihydrochloride, 6-Chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxyacridine dihydrochloride, 866RP, Acrichin dihydrochloride, Atabrine hydrochloride, Atebrin, Atebrine, Atebrine hydrochloride, Chemiochin, Chinacrin hydrochloride, Crinodora, Erion, Malaricida, Mecryl, Mepacrine dihydrochloride, Mepacrine hydrochloride, Methoquine, Metochin, Metoquin, Metoquine, NSC 14229, Palacrin, Palusan, Pentilen, Quinacrine hydrochloride, SN 390, Acridine, 6-chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxy-, dihydrochloride, 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dihydrochloride, 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, hydrochloride (1:2)

Beschreibung

Stability Hygroscopic
Applications Quinacrine 2HCl is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. It is a non-selective MAO-A/B inhibitor.
References Bockelmann, S., et al.: J. Biol. Chem., 285, 38304 (2010); Wrench, A., et al.: PLoS ONE, 8, e54498 (2013); Kasymov, V., et al.: J. Neuroscience, 33, 435 (2013); Mori, T., et al.: Biol. Pharm. Bull., 35, 2243 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 472.88
• Formel: C₂₃H₃₀ClN₃OClH
• Farbe/Form: Neat
• InChl: InChI=1S/C23H30ClN3O.2ClH/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23;;/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26);2*1H
• InChI Key: InChIKey=UDKVBVICMUEIKS-UHFFFAOYSA-N
• SMILES: CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12.Cl.Cl