Raloxifene 4’-Glucuronide

CAS: 182507-22-8

Ref. TR-R100020

Produktinformation

• Name: Raloxifene 4’-Glucuronide
• Synonyme: 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-β-D-glucopyranosiduronic Acid, (4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy-D4]benzoyl]benzo[b]thien-2-yl]phenyl-D-glucopyranosiduronic acid), 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy-d4]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic Acid, 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid, 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-D-glucopyranosiduronicacid, 4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic Acid, Raloxifene-D4-4'-Glucuronide, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-[6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl

Beschreibung

Applications A metabolite of Raloxifene, a nonsteroidal estrogen receptor mixed agonist/antagonist.
References Dodge, J., et al.: Bioorg. Med. Chem. Lett., 7, 993 (1997), Jeong, E., et al.: Drug Metab. Dispos., 33, 785 (2005), Trontelj, J., et al.: Pharmacol. Res., 52, 334 (2005), Oswald, S., et al.: Clin. Pharmacol. Ther., 79 206 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 649.71
• Formel: C₃₄H₃₅NO₁₀S
• Farbe/Form: Neat
• InChl: InChI=1S/C34H35NO10S/c36-21-8-13-24-25(18-21)46-32(20-6-11-23(12-7-20)44-34-30(40)28(38)29(39)31(45-34)33(41)42)26(24)27(37)19-4-9-22(10-5-19)43-17-16-35-14-2-1-3-15-35/h4-13,18,28-31,34,36,38-40H,1-3,14-17H2,(H,41,42)/t28-,29-,30+,31-,34+/m0/s1
• InChI Key: InChIKey=VHXYPEXOSLGZKH-WKRHDJAJSA-N
• SMILES: O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)cc2)sc2cc(O)ccc12