Raloxifene 6-Glucuronide

CAS: 174264-50-7

Ref. TR-R100025

Produktinformation

• Name: Raloxifene 6-Glucuronide
• Synonyme: 2-(4-Hydroxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxybenzoyl]benzo[b]thien-6-yl]-β-D-glucopyranosiduronic Acid, Raloxifene-D4-6'-Glucuronide, 2-(4-Hydroxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxybenzoyl]benzo[b]thien-6-yl]-D-glucopyranosiduronicacid, 2-(4-Hydroxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxybenzoyl]benzo[b]thien-6-yl]-b-D-glucopyranosiduronic Acid, 2-(4-Hydroxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy-d4-benzoyl]benzo[b]thien-6-yl]-b-D-glucopyranosiduronic Acid, Ralaxifene6'-glucuronide, (2-(4-Hydroxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy-D4-benzoyl]benzo[b]thien-6-yl]-D-glucopyranosiduronic acid)

Beschreibung

Applications A metabolite of Raloxifene, a nonsteroidal estrogen receptor mixed agonist/antagonist.
References Dodge, J., et al.: Bioorg. Med. Chem. Lett., 7, 993 (1997), Jeong, E., et al.: Drug Metab. Dispos., 33, 785 (2005), Trontelj, J., et al.: Pharmacol. Res., 52, 334 (2005), Oswald, S., et al.: Clin. Pharmacol. Ther., 79 206 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 649.71
• Formel: C₃₄H₃₅NO₁₀S
• Farbe/Form: Light Yellow To Yellow
• InChl: InChI=1S/C34H35NO10S/c36-21-8-4-20(5-9-21)32-26(27(37)19-6-10-22(11-7-19)43-17-16-35-14-2-1-3-15-35)24-13-12-23(18-25(24)46-32)44-34-30(40)28(38)29(39)31(45-34)33(41)42/h4-13,18,28-31,34,36,38-40H,1-3,14-17H2,(H,41,42)/t28-,29-,30+,31-,34+/m0/s1
• InChI Key: InChIKey=MZPMSLSINDGEPM-WKRHDJAJSA-N
• SMILES: O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)ccc12