Resiquimod-d5

CAS: 2252319-44-9

Ref. TR-R144682

Produktinformation

• Name: Resiquimod-d5
• Synonyme: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol-d5, 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline-d5, 4-Amino-2-ethoxymethyl-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5, R 848-d5, S 28463-d5
• CAS: 2252319-44-9

Beschreibung

Applications Isotope labelled Resiquimod (R144680) is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 319.41
• Formel: C₁₇H₁₇D₅N₄O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)/i1D3,4D2
• InChI Key: InChIKey=BXNMTOQRYBFHNZ-SGEUAGPISA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])OCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O