13-cis-Retinoic Acid-d5

CAS: 4759-48-2

Ref. TR-R250004

Produktinformation

• Name: 13-cis-Retinoic Acid-d5
• Synonyme: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2Z,4E,6E,8E-nonatetranenoic Acid-d5, Isotretinoin-d5, 13-cis-Vitamin A Acid-d5, Accutane-d5, Isotrex-d5, IsotrexGel-d5, Neovitamin A Acid-d5, Ro 4-3780-d5, Roaccutan-d5, Roaccutane-d5, Isotretinoin-d5, (13Cis)-15-Oxidoretinal, (13Z)-Retinoic acid, 13-Cis-Retinoic Acid, 13-Cis-Vitamin A Acid, 13-Ra, 13-cis-β-Retinoic acid, 3,7-Dimethyl-9-(2,6,6-Trimethyl-1-Cyclohexen-1-Yl)-2-Cis-4-Trans-6-Trans-8-Trans-Nonatetraenoic Acid, Absorica, Accure, Accutane, Agn 190013, Amnesteem, Claravis, Isotretinoine, Isotretinoino, Isotrex, IsotrexGel, Neovitamin A acid, Retinoic acid, 13-cis-, Ro 4-3780, Roaccutan, Roaccutane, Roacutan, cis-Retinoic acid

Beschreibung

Applications 13-cis-Retinoic Acid-d5, is the labeled analogue of 13-cis-Retinoic Acid (R250000) used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.
References Lerche, C., et al.: Exp. Dermatol., 17, 972 (2008), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Gan, J., et al.: Chem. Res. Toxicol., 22, 690 (2009), Macejova, D., et al.: Toxicol. Lett., 184, 114 (2009), Chen, P., et al.: Toxicol. App. Pharmacol., 234, 143 (2009),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 305.466
• Formel: C₂₀D₅H₂₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-/i2D3,9D,14D
• InChI Key: InChIKey=SHGAZHPCJJPHSC-FGAPJUHXSA-N
• SMILES: [2H]/C(C(=O)O)=C(C(/[2H])=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)\C([2H])([2H])[2H]