Retrorsine N-Oxide

CAS: 15503-86-3

Ref. TR-R279005

Produktinformation

• Name: Retrorsine N-Oxide
• Synonyme: [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, 12-oxide, (3Z,5R,6S,14aR,14bR)-, Isatidine (6CI,7CI), Retrorsine, N-oxide (8CI), Senecionan-11,16-dione, 12,18-dihydroxy-, 4-oxide, Retrorsine oxide, (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, 14-oxide, (3Z,5R,6S,14aR,14bR)-, (5R,6S,14aR)-3-ethylidene-6-hydroxy-6-(hydroxymethyl)-5-methyl-3,4,5,6,9,11,13,14,14a,14b-decahydro[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 12-oxide, (5R,6S,14aR,14bR)-3-ethylidene-6-hydroxy-6-(hydroxymethyl)-5-methyl-3,4,5,6,9,11,13,14,14a,14b-decahydro[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 12-oxide, 12,18-Dihydroxysenecionan-11,16-dione 4-oxide, Brn 0058804, Ccris 4339, Hsdb 3499, Isatidine, Retrorsine N-oxide, Senecionan-11,16-dione, 12,18-dihydroxy-, 4-oxide, Senecionan-11,16-dione, 12,18-dihydroxy-, 4-oxide (9CI), [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, 12-oxide, (3Z,5R,6S,14aR,14bR)-, cis-Retronecic acid ester of retronecine-N-oxide, trans-15-Ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13beta-methylsenec-1-enine-4-oxide, 4-27-00-06664 (Beilstein Handbook Reference)

Beschreibung

Stability Hygroscopic
Applications Retrorsine N-oxide is a pyrrolizidine alkaloid that is naturally found in Senecio isatideus, a flowering plant that is native to the Netherlands. Retrorsine N-oxide is also known to raise blood pressure and can induce abnormal changes in the liver if ingested by animals or humans.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cooper, R.: Trop. Anim. Health Pro., 39, 439 (2007); Mattocks, A.: Xenobiotica, 1, 563 (1971); Neumann, C. & Boland, W.: Helv. Chim. Acta, 73, 754 (1990); Vera, R., et al.: J. Essent. Oil Res., 6, 21 (1994)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 367.39
• Formel: C₁₈H₂₅NO₇
• Farbe/Form: Neat
• InChl: InChI=1S/C18H25NO7/c1-3-12-8-11(2)18(23,10-20)17(22)25-9-13-4-6-19(24)7-5-14(15(13)19)26-16(12)21/h3-4,11,14-15,20,23H,5-10H2,1-2H3/b12-3-/t11-,14-,15-,18-,19?/m1/s1
• InChI Key: InChIKey=IDIMIWQPUHURPV-WTWIWYCDSA-N
• SMILES: C/C=C1/C[C@@H](C)[C@](O)(CO)C(=O)OCC2=CC[N+]3([O-])CC[C@@H](OC1=O)[C@@H]23