Rilpivirine Glycosamine Product II

Ref. TR-R283410

Produktinformation

• Name: Rilpivirine Glycosamine Product II
• Synonyme: (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)benzonitrile
• Marke: TRC
• Beschreibung: Applications Rilpivirine Glycosamine Product II is an impurity of Rilpivirine(R509800) which is a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.References Sun, et al.: J. Med. Chem., 41, 4648

Chemische Eigenschaften

• Molekulargewicht: 690.7
• Formel: C₃₄H₃₈N₆O₁₀
• Farbe/Form: Neat
• InChl: InChI=1S/C34H38N6O10/c1-17-12-20(4-3-10-35)13-18(2)25(17)38-24-9-11-37-34(39-24)40(21-7-5-19(14-36)6-8-21)32-29(46)28(45)31(23(16-42)48-32)50-33-30(47)27(44)26(43)22(15-41)49-33/h3-9,11-13,22-23,26-33,41-47H,15-16H2,1-2H3,(H,37,38,39)/b4-3+
• SMILES: Cc1cc(/C=C/C#N)cc(C)c1Nc1ccnc(N(c2ccc(C#N)cc2)C2OC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)n1