O-α-D-Glucopyranosyl Rilpivirine

Ref. TR-R354105

Produktinformation

• Name: O-α-D-Glucopyranosyl Rilpivirine
• Synonyme: (E)-4-((4-((4-(2-Cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidin-2-yl)(3,5,6-trihydroxy-2-oxo-4-((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexyl)amino)benzonitrile, Rilpivirine Amadori Rearrangement Product II
• Marke: TRC
• Beschreibung: Applications Rilpivirine Amadori rearrangement Product II is an impurity of Rilpivirine(R509800) which is a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.References Sun, et al.: J. Med. Chem., 41, 4648

Chemische Eigenschaften

• Molekulargewicht: 690.7
• Formel: C₃₄H₃₈N₆O₁₀
• Farbe/Form: Neat
• InChl: InChI=1S/C34H38N6O10/c1-18-12-21(4-3-10-35)13-19(2)27(18)38-26-9-11-37-34(39-26)40(22-7-5-20(14-36)6-8-22)15-23(43)28(45)32(24(44)16-41)50-33-31(48)30(47)29(46)25(17-42)49-33/h3-9,11-13,24-25,28-33,41-42,44-48H,15-17H2,1-2H3,(H,37,38,39)/b4-3+
• SMILES: Cc1cc(/C=C/C#N)cc(C)c1Nc1ccnc(N(CC(=O)C(O)C(OC2OC(CO)C(O)C(O)C2O)C(O)CO)c2ccc(C#N)cc2)n1