Ridaforolimus, >80%

CAS: 572924-54-0

Ref. TR-R495850

Produktinformation

• Name: Ridaforolimus, >80%
• Synonyme: Rapamycin, 42-(dimethylphosphinate) (9CI), AP 23573, Deforolimus, MK 8669, Ridaforolimus
• Marke: TRC
• Beschreibung: Applications An immunosupressant and is currently being investigated for use in cancer treatments. Ridaforolimus may act as a regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival. Ridaforolimus, was formerly known as Deforolimus. Potent mTORC1 inhibitor.References Gadducci, A., et al.: Gynecol. Endocrinol., 24, 239 (2008), Gridelli, C., et al.: Oncol., 13, 139 (2008), Mita, M., et al.: J. Clin. Oncol., 26, 361 (2008), Hartford, C., et al.: Clin. Canc. Res., 15, 1428 (2009),

Chemische Eigenschaften

• Molekulargewicht: 990.21
• Formel: C₅₃H₈₄NO₁₄P
• Reinheit: >80%
• Farbe/Form: Neat
• InChl: InChI=1S/C53H84NO14P/c1-32-18-14-13-15-19-33(2)44(63-8)30-40-23-21-38(7)53(61,67-40)50(58)51(59)54-25-17-16-20-41(54)52(60)66-45(35(4)28-39-22-24-43(46(29-39)64-9)68-69(11,12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15,18-19,27,32,34-36,38-41,43-46,48-49,57,61H,16-17,20-26,28-31H2,1-12H3/b15-13+,18-14+,33-19+,37-27+/t32-,34?,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
• InChI Key: InChIKey=BUROJSBIWGDYCN-GOYCQXJJSA-N
• SMILES: CO[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@@H](OP(C)(C)=O)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C