Ritonavir O-Sulfate

CAS: 2983438-67-9

Ref. TR-R535010

Produktinformation

• Name: Ritonavir O-Sulfate
• Synonyme: (5S,8S,10S,11S)-8,11-Dibenzyl-5-isopropyl-1-(2-isopropylthiazol-4-yl)-2-methyl-3,6,13-trioxo-15-(thiazol-5-yl)-14-oxa-2,4,7,12-tetraazapentadecan-10-yl hydrogen Sulfate

Beschreibung

Applications Ritonavir O-Sulfate is a metabolite of Ritonavir (R535000); a selective HIV protease inhibitor. It is a COVID19-related research product.
References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994); Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005); Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006); Denissen, J.F., et al.: Drug Metab. Dispos., 25, 489 (1997)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 801.01
• Formel: C₃₇H₄₈N₆O₈S₃
• Farbe/Form: Neat
• InChl: InChI=1S/C37H48N6O8S3/c1-24(2)33(42-36(45)43(5)20-29-22-52-35(40-29)25(3)4)34(44)39-28(16-26-12-8-6-9-13-26)18-32(51-54(47,48)49)31(17-27-14-10-7-11-15-27)41-37(46)50-21-30-19-38-23-53-30/h6-15,19,22-25,28,31-33H,16-18,20-21H2,1-5H3,(H,39,44)(H,41,46)(H,42,45)(H,47,48,49)/t28-,31-,32-,33-/m0/s1
• InChI Key: InChIKey=MDZQJEZYNJEVPP-BBPWQIKWSA-N
• SMILES: CC(C)c1nc(CN(C)C(=O)NC(C(=O)NC(Cc2ccccc2)C[C@H](OS(=O)(=O)O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1