Rizatriptan Benzoate

CAS: 145202-66-0

Ref. TR-R545000

Produktinformation

• Name: Rizatriptan Benzoate
• Synonyme: N,N-Dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine benzoate, 1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, benzoate (1:1), 1H-Indole-3-ethanamine, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-, monobenzoate (9CI), MK 462, Maxalt, Rizora
• CAS: 145202-66-0

Beschreibung

Applications Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist and used to treat migraine (1,2,3). It is structurally derived from tryptamine.
References (1) Cheng, H., et al.: Biopharm. Drug Dispos., 17, 17 (1996) (2) Su, M., et al.: Eur J Neurosci. 44, 2129 (2016)(3) Millson, D. S., et al.: Expert Opin Pharmacother. 1, 391 (2000)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 391.47
• Formel: C₂₂H₂₅N₅O₂
• Farbe/Form: Light Yellow
• InChl: InChI=1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20, 1-5H,(H,8,9), 8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3
• InChI Key: InChIKey=JPRXYLQNJJVCMZ-UHFFFAOYSA-N
• SMILES: CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12.O=C(O)c1ccccc1