RO 2433

CAS: 863329-66-2

Ref. TR-R637200

Produktinformation

• Name: RO 2433
• Synonyme: 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, GS 331007, PSI-6206, Sofosbuvir Nucleoside Derivative, Sofosbuvir metabolite, (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine, (2'R)-2'-deoxy-2'-fluoro-2'-methyl-Uridine, (2R)-2-Deoxy-2-fluoro-2-methyluridine, 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 2'-Deoxy-2'-Fluoro-2'-C-Methyl Uridine, 2'-Deoxy-2'-Fluoro-2'-Methyluridine, 2-Deoxy-2-Fluoro-2-Methyl Uridine, Gs 331007, Psi-6206, Ro 2433, Sofosbuvir N-1, Uridine, 2′-deoxy-2′-fluoro-2′-methyl-, (2′R)-

Beschreibung

Impurity Sofosbuvir Metabolite GS331007
Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.
References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 260.22
• Formel: C₁₀H₁₃FN₂O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C10H13FN2O5/c1-10(11)7(16)5(4-14)18-8(10)13-3-2-6(15)12-9(13)17/h2-3,5,7-8,14,16H,4H2,1H3,(H,12,15,17)/t5-,7-,8-,10-/m1/s1
• InChI Key: InChIKey=LTRRZXWSQLKVFA-HEGZNORDSA-N
• SMILES: CCOC(C)OCC(=O)[C@]1(O)CC[C@@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@]3(F)[C@@H](O)C[C@@]21C