Rosiglitazone Maleate

CAS: 155141-29-0

Ref. TR-R693500

Produktinformation

• Name: Rosiglitazone Maleate
• Synonyme: 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (2Z)-2-butenedioate (1:1), 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (Z)-2-butenedioate (1:1), 5-[[4-[2-(N-Methyl-N-2-pyridylamino)ethoxy]phenyl]methyl]thiazolidine-2,4-dione maleate, Avandia, BRL 49653C, BRL-49653C, SB214521, SB236833, SB237216, BRL 49653C, 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (2Z)-2-butenedioate (1:1), 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (Z)-2-butenedioate (1:1), 5-{p-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate, Brl 49653C, Rosigliazone maleate, Rosiglitazone maleate

Beschreibung

Applications Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ).
References Cantello, B.C.C., et al.: J. Med. Chem., 37, 3977 (1994), Oakes, N.D., et al.: Diabetes, 43, 1203 (1994), Balton, G.C., et al.: Xenobiotica, 26, 627 (1996), Barman, J.A., et al.: Drugs, 57, 921 (1999),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 473.50
• Formel: C₁₈H₁₉N₃O₃S·C₄H₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI Key: InChIKey=SUFUKZSWUHZXAV-BTJKTKAUSA-N
• SMILES: CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1.O=C(O)/C=C\C(=O)O