ent-Rosuvastatin Sodium Salt

CAS: 1242184-42-4

Ref. TR-R700515

Produktinformation

• Name: ent-Rosuvastatin Sodium Salt
• Synonyme: (3S,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt, (3S,5R)-Rosuvastatin Sodium Salt, Rosuvastatin EP Impurity G Sodium Salt
• Marke: TRC
• Beschreibung: Impurity Rosuvastatin EP Impurity GStability HygroscopicApplications ent-Rosuvastatin is an enantiomer of Rosuvastatin (R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor (1). Antilipemic (2,3).References 1. Watanabe, M. et al.: Bioorg. Med. Chem. 1997 Feb;5(2):437-44.2. Lee, E. et al.: Clin. Pharmacol. Ther. 2005 Oct;78(4):330-41.3. Ferdinand, C. et al.: Am. J. Cardiol. 2006 Jan 15;97(2):229-35.

Chemische Eigenschaften

• Molekulargewicht: 503.52
• Formel: C₂₂H₂₇FN₃NaO₆S
• Farbe/Form: Neat
• InChl: InChI=1S/C22H28FN3O6S.Na/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;+1/p-1/b10-9+;/t16-,17-;/m0./s1
• SMILES: CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@H](O)C[C@H](O)CC(=O)[O-].[Na+]