(2S,4R)-Sacubitril

CAS: 761373-05-1

Ref. TR-S080905

Produktinformation

• Name: (2S,4R)-Sacubitril
• Synonyme: [1,1'-Biphenyl]-4-pentanoic acid, ?-[(3-carboxy-1-oxopropyl)amino]-a-methyl-, 4-ethyl ester, (aS,?R)-, [1,1'-Biphenyl]-4-pentanoic acid, ?-[(3-carboxy-1-oxopropyl)amino]-a-methyl-, a-ethyl ester, [R-(R*,S*)]- (9CI), (2S,4R)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic acid ethyl ester, (2S,4R)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester
• CAS: 761373-05-1

Beschreibung

Stability Temperature Sensitive
Applications (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.
References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 411.49
• Formel: C₂₄H₂₉NO₅
• Farbe/Form: Colourless To Off-White
• InChl: InChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21+/m0/s1
• InChI Key: InChIKey=PYNXFZCZUAOOQC-LAUBAEHRSA-N
• SMILES: CCOC(=O)[C@@H](C)C[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)CCC(=O)O