Saralasin

CAS: 34273-10-4

Ref. TR-S142510

Produktinformation

• Name: Saralasin
• Synonyme: Saralasin,L-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl- (9CI, ACI), Angiotensin II, 1-(N-methylglycine)-5-L-valine-8-L-alanine- (ZCI), Angiotensin II, 1-sarcosine-5-L-valine-8-L-alanine- (8CI), N-Methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl-L-alanine (ACI), 1-Sar-5-Val-8-Ala-angiotensin II, 1-Sar-8-ala-angiotensin II, [1-Sarcosine-5-valine-8-alanine]angiotensin II, Aralasin, P 113, P 113 (angiotensin II derivative), (1-(N-Methylglycin) 5-L-valin, 8-L-alanin)angiotensin II, N-(1-(N-(N-(N-(N-(N2-(N-methylglycly)-L-arginyl)-L-valyl)-L-tyrosyl)-L-valyl)-L-histidyl)-L-prolyl)-L-alanine, Saralasina, Saralasina [INN-Spanish], Saralasine, Saralasine [INN-French], Saralasinum, Saralasinum [INN-Latin], Unii-H2Afv2He66, Angiotensin II, 1-(N-methylglycine)-5-L-valine-8-L-alanine-, N-methylglycyl-N~5~-(diaminomethylidene)ornithylvalyltyrosylvalylhistidylprolylalanine, N-methylglycyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl-L-alanine

Beschreibung

Applications Saralasin are angiotensin II receptor agonists.
References Guimond, M., et al.: J. Med. Chem. Lett., 5, 1129 (2014)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 912.047
• Formel: C₄₂H₆₅N₁₃O₁₀
• Farbe/Form: Neat
• InChl: InChI=1S/C42H65N13O10/c1-22(2)33(53-35(58)28(50-32(57)20-45-6)9-7-15-47-42(43)44)38(61)51-29(17-25-11-13-27(56)14-12-25)36(59)54-34(23(3)4)39(62)52-30(18-26-19-46-21-48-26)40(63)55-16-8-10-31(55)37(60)49-24(5)41(64)65/h11-14,19,21-24,28-31,33-34,45,56H,7-
• InChI Key: InChIKey=PFGWGEPQIUAZME-NXSMLHPHSA-N
• SMILES: CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C)C(C)C