D-erythro-Sphingosine-1-phosphate

CAS: 26993-30-6

Ref. TR-S681500

Produktinformation

• Name: D-erythro-Sphingosine-1-phosphate
• Synonyme: [(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enyl] dihydrogen phosphate
• Marke: TRC
• Beschreibung: Stability Moisture, Temperature Sensitive; HygroscopicApplications A putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes. It mobilizes intracellular calcium stores, decreases cellular cAMP, activates phospholipase D and does not inhibitprotein kinase C.References Yeh, C., et al.: Am. J. Physiol., 296, H1193 (2009), Hagen, N., et al.: J. Biol. Chem., 284, 11346 (2009), Kuehnel, M., et al.: J. Cell Sci., 122, 499 (2009),

Chemische Eigenschaften

• Molekulargewicht: 379.47
• Formel: C₁₈H₃₈NO₅P
• Farbe/Form: Neat
• InChl: InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
• InChI Key: InChIKey=DUYSYHSSBDVJSM-NVGHFZOBSA-N
• SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](N)COP(=O)(O)O