Spironolactone-d7 (Major)

CAS: 52-01-7

Ref. TR-S683002

Produktinformation

• Name: Spironolactone-d7 (Major)
• Synonyme: (7α,7α)-7-Acetylthyo-17-hydroxy-3-oxopregn-4-one-21-carboxylic Acid γ-Lactone-d7, 7α-Acetylthio-3-oxo-17α-pregn-4-ene-21,17-carbolactone-d7, SC-9420-d7
• Marke: TRC
• Beschreibung: Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome. A representative lot was 19% d3; 47% d6; 12% d7; 7% d8; 3% d9; 3% d10 and 8% d11.References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),

Chemische Eigenschaften

• Molekulargewicht: 423.62
• Formel: C₂₄H₂₅D₇O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C23H32O3S/c1-21-8-4-15(24)12-14(21)13-18(27-3)20-16(21)5-9-22(2)17(20)6-10-23(22)11-7-19(25)26-23/h12,16-18,20H,4-11,13H2,1-3H3/t16-,17-,18+,20+,21-,22-,23+/m0/s1/i4D2,7D2,12D,13D2
• InChI Key: InChIKey=LXMSZDCAJNLERA-FAQYADQFSA-N
• SMILES: [2H]C1=C2[C@@H]([2H])[C@@]([2H])(SC(C)=O)[C@H]3[C@@H]4CC[C@@]5(CC([2H])([2H])C(=O)O5)[C@@]4(C)CC[C@@H]3[C@@]2(C)CC([2H])([2H])C1=O