Suberoylanilide-d5 Hydroxamic Acid

CAS: 1132749-48-4

Ref. TR-S688702

Produktinformation

• Name: Suberoylanilide-d5 Hydroxamic Acid
• Synonyme: SAHA-d5, N-Hydroxy-N’-phenyl-d5-octanediamide, Zolinza-d5, Vorinostat-d5

Beschreibung

Applications A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells.
References Richon, V.M., et al.: Proc. Natl. Acad.Sci. USA, 95, 3003 (1988), Munster, P.N., et al.: Cancer Res., 61, 8492 (2001), Deroanne, C.F., et al.: Oncogene, 21, 247 (2002),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 269.35
• Formel: C₁₄H₁₅D₅N₂O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)/i3D,4D,5D,8D,9D
• InChI Key: InChIKey=WAEXFXRVDQXREF-YQYLVRRTSA-N
• SMILES: [2H]c1c([2H])c([2H])c(NC(=O)CCCCCCC(=O)NO)c([2H])c1[2H]