Tacrolimus Methyl Acryl Aldehyde

CAS: 109466-74-2

Ref. TR-T004150

Produktinformation

• Name: Tacrolimus Methyl Acryl Aldehyde
• Synonyme: 2-Propenal, 3-(4-hydroxy-3-methoxycyclohexyl)-2-methyl-, [1R-[1a(E),3a,4ß]]- (9CI)
• CAS: 109466-74-2

Beschreibung

Impurity Tacrolimus Methylacryl Aldehyde (USP)
Applications Tacrolimus Methyl Acryl Aldehyde is the degradation product of Tacrolimus (F370000), a novel macrocyclic lactone isolated from Streptomyces tsukubaensis, having immunosuppressant activity.
References Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 198.26
• Formel: C₁₁H₁₈O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C11H18O3/c1-8(7-12)5-9-3-4-10(13)11(6-9)14-2/h5,7,9-11,13H,3-4,6H2,1-2H3/b8-5+/t9-,10+,11+/m0/s1
• InChI Key: InChIKey=ZTXGCGOIEHBZMQ-OJHBQYHASA-N
• SMILES: CO[C@@H]1C[C@H](/C=C(\C)C=O)CC[C@H]1O