Tarceva (Erlotinib Hydrochloride)

CAS: 183319-69-9

Ref. TR-T007500

Produktinformation

• Name: Tarceva (Erlotinib Hydrochloride)
• Synonyme: OSI 774, Tarceva,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, [6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride, CP 358774, Erlotinib hydrochloride, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride
• Marke: TRC
• Beschreibung: Applications Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.References Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001), Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004), Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005),

Chemische Eigenschaften

• Molekulargewicht: 429.90
• Formel: C₂₂H₂₃N₃O₄·ClH
• Farbe/Form: Neat
• InChl: InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22, 1H, /h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
• InChI Key: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1.Cl