Taurolithocholic Acid Sodium Salt

CAS: 6042-32-6

Ref. TR-T009100

Produktinformation

• Name: Taurolithocholic Acid Sodium Salt
• Synonyme: Ethanesulfonic acid, 2-[[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1), Ethanesulfonic acid, 2-[[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]amino]-, monosodium salt (9CI), Taurine, N-(3α-hydroxy-5β-cholan-24-oyl)-, monosodium salt (8CI), Taurolithocholic acid, sodium salt (6CI,7CI), NSC 681057, Sodium taurolithocholate, 2-[[(3α,5β)-3-Hydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid sodium salt
• Marke: TRC

Beschreibung

Stability Hygroscopic
Applications The major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
References Javitt, N.B., et al.: J. Clin. Invest., 47, 1002 (1968), Bowmer, C., et al.: J. Pharm. Pharmacol., 37, 812 (1985), Ha, C., et al.: J. Biomed. Sci., 7, 114 (2000), Zaton, A., et al.: Chem. Biol. Interact., 124, 1 (2000),

Chemische Eigenschaften

• Molekulargewicht: 505.69
• Formel: C₂₆H₄₄NO₅S·Na
• Farbe/Form: Neat
• InChl: InChI=1S/C26H45NO5S.Na/c1-17(4-9-24(29)27-14-15-33(30,31)32)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3;/h17-23,28H,4-16H2,1-3H3,(H,27,29)(H,30,31,32);/q;+1/p-1/t17-,18-,19-,20+,21-,22+,23+,25+,26-;/m1./s1
• SMILES: C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C.[Na+]