Telbivudine

CAS: 3424-98-4

Ref. TR-T016000

Produktinformation

• Name: Telbivudine
• Synonyme: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-ß-L-erythro-pentofuranosyl)-5-methyl-, Thymine, 1-(2-deoxy-ß-L-erythro-pentofuranosyl)- (7CI,8CI), 1-(2-Deoxy-ß-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 2'-Deoxy-L-thymidine, Epavudine, L-Deoxythymidine, L-Thymidine, NV 02B, Sebivo, Tyzeka, ß-L-Thymidine, 1-(2-Deoxy--L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 1-(2-Deoxy-β-<span class="text-smallcaps">L</span>-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 1-(2-deoxy--L-erythro-pentofuranosyl)thymine, 1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">L</span>-erythro-pentofuranosyl)-5-methyl-, 2′-Deoxy-<span class="text-smallcaps">L</span>-thymidine, <span class="text-smallcaps">L</span>-Deoxythymidine, <span class="text-smallcaps">L</span>-Thymidine, Beta-L-Thymidine, Nv 02B, Telbivudine & its intermediates, Telbivudine intermediates, Thymine, 1-(2-deoxy-β-<span class="text-smallcaps">L</span>-erythro-pentofuranosyl)-, β-<span class="text-smallcaps">L</span>-Thymidine

Beschreibung

Applications Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.
References Standring, D.N., et al.: Antiviral. Chem. Chemother., 12, 119 (2001), Hernandez-Santiago, B., et al.: Antimicrob. Agents Chemother., 46, 1728 (2002), Lai, C.-L., et al.: Hepatology, 40, 719 (2004), Han, S.-H.B., et al.: Expert Opin. Invest. Drugs, 14, 511 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 242.23
• Formel: C₁₀H₁₄N₂O₅
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
• InChI Key: InChIKey=IQFYYKKMVGJFEH-CSMHCCOUSA-N
• SMILES: Cc1cn([C@@H]2C[C@@H](O)[C@H](CO)O2)c(=O)nc1O