Telocinobufogenin

CAS: 472-26-4

Ref. TR-T017060

Produktinformation

• Name: Telocinobufogenin
• Synonyme: 5-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]pyran-2-one, (3Beta,5Beta)-3,5,14-Trihydroxybufa-20,22-Dienolide, (3β,5β)-3,5,14-Trihydroxybufa-20,22-dienolide, 3Β,5,14-Trihydroxy-5Β-Bufa-20,22-Dienolide, 5.beta.-Bufa-20,22-dienolide, 3.beta.,5,14-trihydroxy-, 5β-Bufa-20,22-dienolide, 3β,5,14-trihydroxy-, Bufa-20,22-Dienolide, 3,5,14-Trihydroxy-, (3Beta,5Beta)-, Bufa-20,22-Dienolide, 3,5,14-Trihydroxy-, (3Beta,5Beta,8Xi,9Xi)-, Bufa-20,22-dienolide, 3,5,14-trihydroxy-, (3.beta.,5.beta.)-, Bufa-20,22-dienolide, 3,5,14-trihydroxy-, (3β,5β)-, NSC 119989, NSC 90782, Telecinobufagin, Telobufotoxin, Telocinobufagin

Beschreibung

Applications Telocinobufagin is isolated as a major component from skin secretion of the toad Bufo rubescens. Telocinobufogenin is a novel antibiotic cardiotonic.
References Akizawa, T., et al.: Chem. Pharm. Bull., 42, 754 (1994); Hancock, R., et al.: Antimicrob. Agents Chemother., 43, 1317 (1999); Jing, Y., et al.: J. Cancer Res., 85, 645 (1994); Kamano, Y., et al.: J. Med. Chem., 45, 5440 (2002); Schoner, W., et al.: Eur. J. Biochem., 269, 2440 (2002); Cunha Filho, G., et al.: Toxicon, 45, 777 (2005)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 402.52
• Formel: C₂₄H₃₄O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C24H34O5/c1-21-9-5-16(25)13-23(21,27)11-7-19-18(21)6-10-22(2)17(8-12-24(19,22)28)15-3-4-20(26)29-14-15/h3-4,14,16-19,25,27-28H,5-13H2,1-2H3/t16-,17+,18-,19+,21+,22+,23-,24-/m0/s1
• InChI Key: InChIKey=KWOLFJPFCHCOCG-UHFFFAOYSA-N
• SMILES: CC(=O)c1ccccc1