Tenidap

CAS: 120210-48-2

Ref. TR-T018330

Produktinformation

• Name: Tenidap
• Synonyme: 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-, 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (Z)-, (3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide, CP 66248, (Z)-5-Chloro-3-(alpha-hydroxy-2-thenylidene)-2-oxo-1-indolinecarboxamide, 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-, 1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (Z)-, 5-chloro-2-hydroxy-3-(thiophen-2-ylcarbonyl)-1H-indole-1-carboxamide, 5-chloro-2-oxo-3-(thiophen-2-ylcarbonyl)-2,3-dihydro-1H-indole-1-carboxamide, Cp 66,248, Tenidap [USAN:INN:BAN], Tenidapum, Tenidapum [INN-Latin], Unii-9K7Cj74Onh

Beschreibung

Applications Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.
References Moilanen, et al.: Eicosanoids, 1, 35 (1988), Kirchner, et al.: J. Pharmacol. Exp. Ther., 282, 1094 (1997), Liu, et al.: Eur. J. Pharmacol., 435, 153 (2002),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 320.75
• Formel: C₁₄H₉ClN₂O₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11-
• InChI Key: InChIKey=LXIKEPCNDFVJKC-QXMHVHEDSA-N
• SMILES: NC(=O)N1C(=O)/C(=C(\O)c2cccs2)c2cc(Cl)ccc21