rac Tenofovir-d6

CAS: 1020719-94-1

Ref. TR-T018502

Produktinformation

• Name: rac Tenofovir-d6
• Synonyme: P-[[1-[(6-amino-9H-purin-9-yl)methyl-d2]ethoxy-1,2,2,2-d4]methyl]phosphonic acid

Beschreibung

Applications A deuterated acyclic phosphonate nucleotide analogue, reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 293.25
• Formel: C₉H₆H₈N₅O₄P
• Farbe/Form: Off White Solid
• InChl: InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/i1D3,2D2,6D
• InChI Key: InChIKey=SGOIRFVFHAKUTI-CUYPRXAISA-N
• SMILES: [2H]C([2H])([2H])C([2H])(OCP(=O)(O)O)C([2H])([2H])n1cnc2c(N)ncnc21