Tert-butyl 2-[(4R,6S)-2,2-Dimethyl-6-[(methylcarbonyloxy)methyl]-1,3-dioxan-4-yl]acetate

CAS: 154026-95-6

Ref. TR-T117700

Produktinformation

• Name: Tert-butyl 2-[(4R,6S)-2,2-Dimethyl-6-[(methylcarbonyloxy)methyl]-1,3-dioxan-4-yl]acetate
• Synonyme: 2-[(4R,6S)-6-(Acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid Tert-butyl Ester, [(4R,6S)-6-Acetoxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]acetic Acid Tert-butyl Ester, (4R-Cis)-6-[(Acetyloxy) methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Diemthyethyl Ester, (4R-Cis)-6-[(Acetyloxy) methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Dimethyethyl Ester, (4R-Cis)-6-[(Acetyloxy)Methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester, (4R-Cis)-6-[(Acetyloxy)Methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid, T-Butyl Ester, (4R-Cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-diox ane-4-acetic acid,1,1-dimethylethyl ester, (4R-Cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester(D5), (4R-Cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-yl] acetic acid tert-butyl ester, (4r-Cis)6[(Acetyloxymethyl)]-2,2-Dimethyl-1,3-Dimethyl-1,3-Dioxane-4-Acetic Acid, 1,1-Dimethylethyl Ester, 2-[(4R,6S)-6-(Acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-buthyl ester, 2-[(4R,6S)-6-(Acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid tert-butyl ester, <span class="text-smallcaps">D</span>-erythro-Hexonic acid, 2,4-dideoxy-3,5-O-(1-methylethylidene)-, 1,1-dimethylethyl ester, 6-acetate, <span class="text-smallcaps">D</span>-erythro-Hexonic acid, 2,4-dideoxy-3,5-O-(1-methylethylidene)-, 1,1-dimethylethyl ester, acetate, D-5, D5, Rosuvastatin calcium intermediate C-1, Rosuvastatin intermediates D-5, [(4R,6S)-6-Acetoxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl]acetic acid tert-butyl ester, rosuvastatin intermediates C-4, tert-Butyl 2-[(4R,6S)-2,2-dimethyl-6-[(methylcarbonyloxy)methyl]-1,3-dioxan-4-yl]acetate, tert-butyl 6-O-acetyl-2,4-dideoxy-3,5-O-(1-methylethylidene)-D-erythro-hexonate

Beschreibung

Impurity Rosuvastatin Impurity 19
Applications Tert-butyl 2-[(4R,6S)-2,2-Dimethyl-6-[(methylcarbonyloxy)methyl]-1,3-dioxan-4-yl]acetate (Rosuvastatin Impurity 19) is an impurity of Rosuvastatin (R700500), a selective and competitive HMG-CoA reductase inhibitor.
References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 302.36
• Formel: C₁₅H₂₆O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C18H29N3O4S/c1-5-21-9-7-8-13(21)12-20-18(22)14-10-17(26(23,24)6-2)15(19-3)11-16(14)25-4/h10-11,13,19H,5-9,12H2,1-4H3,(H,20,22)
• InChI Key: InChIKey=NXKXZXNNWRYXRE-UHFFFAOYSA-N
• SMILES: CCN1CCCC1CNC(=O)c1cc(S(=O)(=O)CC)c(NC)cc1OC