Tenofovir Monohydrate

CAS: 206184-49-8

Ref. TR-T185533

Produktinformation

• Name: Tenofovir Monohydrate
• Synonyme: [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid;hydrate, (R)-9-(2-phosphonylmethoxy propyl)adenine, (R)-9-(2-phosphonylmethoxypropyl)adenine, (R)-[[2-(6-Amino-9H-Purin-9-Yl)-1-Methylethoxy]Methyl]-Phosphonic Acid Monohydrate, 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate, Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, hydrate (1:1), Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monohydrate, Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monohydrate, (R)-, Tenofovir monohydrate[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid monohydrate, {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonic acid hydrate

Beschreibung

Stability Hygroscopic
Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.
References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 305.23
• Formel: C₉H₁₄N₅O₄P·H₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C9H14N5O4P.H2O/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14;/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17);1H2/t6-;/m1./s1
• InChI Key: InChIKey=BTTWKVFKBPAFDK-QAZMUZRASA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CCC4=C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@H]2O