3β,5α-Tetrahydrodeoxycorticosterone

CAS: 567-01-1

Ref. TR-T293290

Produktinformation

• Name: 3β,5α-Tetrahydrodeoxycorticosterone
• Synonyme: Pregnan-20-one, 3,21-dihydroxy-, (3ß,5a)-, 5a-Pregnan-20-one, 3ß,21-dihydroxy- (8CI), (3ß,5a)-3,21-Dihydroxypregnan-20-one, 3ß,21-Dihydroxy-5a-pregnan-20-one, 3ß,5a-Tetrahydrodeoxycorticosterone, (3ß,5a)- 3,21-Dihydroxypregnan-20-one, Epiallopregnanolone

Beschreibung

Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.
References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 334.49
• Formel: C₂₁H₃₄O₃
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C21H34O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h13-18,22-23H,3-12H2,1-2H3/t13-,14-,15-,16-,17-,18+,20-,21-/m0/s1
• InChI Key: InChIKey=CYKYBWRSLLXBOW-VTBMCCKRSA-N
• SMILES: C[C@]12CC[C@H](O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)CO)CC[C@@H]12