1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)

CAS: 99614-03-6

Ref. TR-T293715

Produktinformation

• Name: 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
• Synonyme: Ondansetron Hydrochloride Dihydrate Imp. G (EP), Ondansetron Imp. G (EP), (3RS)-3-[(1H-Imidazol-1-yl)methyl]-9-methyl-1,2,3,9-tetrahydro-4H-carbazol-4-one, C-Demethylondansetron, Ondansetron Hydrochloride Dihydrate Impurity G, Ondansetron Impurity G
• CAS: 99614-03-6

Beschreibung

Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.
References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 279.34
• Formel: C₁₇H₁₇N₃O
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C17H17N3O/c1-19-14-5-3-2-4-13(14)16-15(19)7-6-12(17(16)21)10-20-9-8-18-11-20/h2-5,8-9,11-12H,6-7,10H2,1H3
• InChI Key: InChIKey=KPSGSRBENRBWPG-UHFFFAOYSA-N
• SMILES: Cn1c2c(c3ccccc31)C(=O)C(Cn1ccnc1)CC2