4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid

CAS: 153559-46-7

Ref. TR-T294945

Produktinformation

• Name: 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
• Synonyme: 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)carbonyl]benzoic acid, LG 100064, Desmethylene Oxo-bexarotene, Benzoic acid, 4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]-, 4-[(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Carbonyl]Benzoic Acid
• CAS: 153559-46-7

Beschreibung

Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.
References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 350.45
• Formel: C₂₃H₂₆O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-6-8-16(9-7-15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)
• InChI Key: InChIKey=QADGBOQVBUXZKO-UHFFFAOYSA-N
• SMILES: Cc1cc2c(cc1C(=O)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C