3’-β-Thymidine

CAS: 16053-52-4

Ref. TR-T412005

Produktinformation

• Name: 3’-β-Thymidine
• Synonyme: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-ß-D-threo-pentofuranosyl)-5-methyl-, Thymine, 1-(2-deoxy-ß-D-threo-pentofuranosyl)- (7CI,8CI), 1-(2-Deoxy-ß-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 1-(2'-Deoxy-ß-D-threo-pentofuranosyl)thymine, N, 1-(2'-Deoxy-beta-D-threo-pentofuranosyl)thymine, 1-Dpft, 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-threo-pentofuranosyl)-5-methyl-, 1-(2-deoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(2-deoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

Beschreibung

Impurity Stavudine EP Impurity B
Applications 3’-β-Thymidine (Stavudine EP Impurity B) is an intermediate in the production of fluorothymidine and phosphorylase derivatives (1,2). Stavudine is used as an antiviral agent. Reverse transcriptase inhibitor (3).
References 1. Roberta, G. et al.: Biochem. Pharmacol. 1993 Dec 14;46(12):2209-18.2. Hatano, A. et al.: Bioorg. Med. Chem. 2008 Apr 1;16(7):3866-703. Santiprabhob, J. et al.: Biomed. Res. Int. 2017;2017:7481597.

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 242.229
• Formel: C₁₀H₁₄N₂O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7-,8-/m1/s1
• InChI Key: InChIKey=UCPVOTSNNAVKNE-LMOVPXPDSA-N
• SMILES: Cl.O=C(O)CCCN1CCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1