Thyroxine 4’-O-Beta-D-Glucuronide

CAS: 21462-56-6

Ref. TR-T425630

Produktinformation

• Name: Thyroxine 4’-O-Beta-D-Glucuronide
• Synonyme: 4-[4-[(2S)-2-Amino-2-carboxyethyl]-2,6-diiodophenoxy]-2,6-diiodophenyl ß-D-Glucopyranosiduronic ccAcid, Levothyroxine Phenolic Glucuronide, (S)-4-[4-(2-Amino-2-carboxyethyl)-2,6-diiodophenoxy]-2,6-diiodophenyl ß-D-Glucopyranosiduronic Acid, L-Thyroxine Glucuronide, Thyroxine Glucuronide

Beschreibung

Applications Thyroxine 4-O-β-D-Glucuronide is a major metabolite and glucuronide conjugate of Thyroxine (T425600) formed via the glucuronidation of the phenyl hydroxyl group.
References Tong, Z. et al.: Drug Metab. Dispos., 35, 2203 (2007); West, C.D. et al.: J. Clin. INvest., 42, 1134 (1963);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 952.99
• Formel: C₂₁H₁₉I₄NO₁₀
• Farbe/Form: Off-White
• InChl: InChI=1S/C21H19I4NO10/c22-8-1-6(3-12(26)19(30)31)2-9(23)16(8)34-7-4-10(24)17(11(25)5-7)35-21-15(29)13(27)14(28)18(36-21)20(32)33/h1-2,4-5,12-15,18,21,27-29H,3,26H2,(H,30,31)(H,32,33)/t12-,13-,14-,15+,18-,21+/m0/s1
• InChI Key: InChIKey=RGHRJBIKIYUHEV-OBOXGAGSSA-N
• SMILES: N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)c(I)c2)c(I)c1)C(=O)O