Tiagabine Hydrochloride

CAS: 145821-59-6

Ref. TR-T436400

Produktinformation

• Name: Tiagabine Hydrochloride
• Synonyme: (3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid hydrochloride, (R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid hydrochloride, ABT 569, Abbott 70569 hydrochloride, Abbott 70569.1, Gabitril, NNC 05-0328, NO 05-0328, Tiabex, (3R)-1-[4,4-Bis(3-methylthien-2-yl)-3-butenyl]piperidine-3-carboxylic acid hydrochloride, (3R)-1-[4,4-Bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylic acid hydrochloride, (3R)-1-[4,4-Bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid hydrochloride, (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl]piperidine-3-carboxylic acid hydrochloride (1:1), 3-Piperidinecarboxylic acid, 1-[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]-, hydrochloride (1:1), (3R)-, 3-Piperidinecarboxylic acid, 1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-, hydrochloride, (3R)-, 3-Piperidinecarboxylic acid, 1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-, hydrochloride, (R)-, Abt 569, Nnc 05-0328, No 05-0328

Beschreibung

Applications Tiagabine Hydrochloride is a GABA uptake inhibitor and an anticonvulsant (1,2,3). It is used to treat epilepsy, anxiety disorders, and panic disorder. Neuroprotective & Neuroresearch Product.
References (1) Andersen, K.E., et al.: J. Med. Chem., 36, 1716 (1993)(2) Fangold, C.L., et al.: Exp. Neurology, 126, 225 (1994) (3) Bauer, J., et al.: J. Epilepsy, 8, 83 (1995)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 412.01
• Formel: C₂₀H₂₅NO₂S₂·ClH
• Farbe/Form: Neat
• InChl: InChI=1S/C20H25NO2S2.ClH/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23;/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23);1H/t16-;/m1./s1
• InChI Key: InChIKey=YUKARLAABCGMCN-PKLMIRHRSA-N
• SMILES: Cc1ccsc1C(=CCCN1CCC[C@@H](C(=O)O)C1)c1sccc1C.Cl