δ 4-Tibolone

CAS: 1162-60-3

Ref. TR-T437505

Produktinformation

• Name: δ 4-Tibolone
• Synonyme: (7R,8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-7,13-dimethyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one, (7Alpha)-17-Ethynyl-17-Hydroxy-7-Methylestr-4-En-3-One, (7a,17a)-17-Hydroxy-7-methyl-19-norpregn-4-en-20-yn-3-one, 17-Ethynyl-17-Hydroxy-7-Methylestr-4-En-3-One, 17a-Ethynyl-17-hydroxy-7a-methyl-4-estren-3-one, 17β-Hydroxy-17α-ethynyl-7α-methylestr-4-en-3-one, 19-Nor-17α-pregn-4-en-20-yn-3-one, 17-hydroxy-7α-methyl-, 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-7-methyl-, (7α,17α)-, 7a-Methylnorethindrone, 7α-Methyl-17α-ethynyl-19-nortestosterone, Isotibolone, Nsc 142228, Org-OM 38, Δ⁴-Tibolone

Beschreibung

Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.
References Clarkson, T., et al.: J. Clin. Endocrinol. Metab., 86, 5396 (2001), Landgren, M., et al.: Maturitas, 50, 222 (2005), Wang, M., et al.: Steroids, 71, 343 (2006), Verheul, H., et al.: Drug Metab. Dispos., 35, 1105 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 312.45
• Formel: C₂₁H₂₈O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C21H28O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,12-13,16-19,23H,5-11H2,2-3H3/t13-,16+,17-,18+,19-,20+,21+/m1/s1
• SMILES: C#C[C@]1(O)CC[C@H]2[C@H]3[C@H](CC[C@@]21C)[C@H]1CCC(=O)C=C1C[C@H]3C